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Bronchogen is a Khavinson bioregulator tetrapeptide (AEDL) with primary effects on the bronchopulmonary system. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology by Professor Vladimir Khavinson, it targets bronchial tissue and supports respiratory function. Like other Khavinson peptides, Bronchogen penetrates cell nuclei to influence gene expression related to respiratory tissue maintenance and repair.

Chonluten is a Khavinson bioregulator tripeptide (EDG) derived from respiratory lung tissue. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it targets the bronchopulmonary system with secondary activity in the GI tract. Research shows it regulates genes related to inflammation, antioxidant activity, and proliferation responses. Chonluten inhibits TNF production in monocytes and has been studied as a potential geroprotective agent that may support lung function in conditions like COPD.

Crystagen is a Khavinson bioregulator tripeptide (EDP) identified in thymalin with selective action on thymus tissues. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it enhances immune function by stimulating normal lymphocyte proliferation while inhibiting tumor cell growth. Research shows effectiveness in normalizing immunity in 82% of elderly patients (vs 56% control) and reducing respiratory infections in athletes by doubling HSP gene expression.

Epitalon is a synthetic tetrapeptide developed by Russian scientist Vladimir Khavinson with 35+ years of research. It activates telomerase at extremely low concentrations to maintain telomere length, stimulates melatonin production, and modulates gene expression through epigenetic mechanisms.

Glutathione is the body's master antioxidant, a tripeptide produced naturally by the liver. It protects cells against free radicals, peroxides, and heavy metals while eliminating toxins including drugs and pollutants. Injectable glutathione bypasses gastrointestinal breakdown for superior bioavailability compared to oral supplements. Research supports benefits for neurological health, immune function, skin health, and anti-aging.

KPV is a potent anti-inflammatory tripeptide derived from the C-terminal of alpha-MSH. It exhibits remarkable anti-inflammatory and antimicrobial properties without the pigmentation effects of full α-MSH, making it ideal for inflammation management.

Livagen is a Khavinson bioregulator tetrapeptide (KEDA) with significant hepatoprotective and immunomodulatory properties. Structurally similar to Epitalon, it normalizes immune and antioxidant status while restoring liver function in hepatitis conditions. Livagen is best known for its ability to decondense chromatin, activating silent genes including ribosomal genes to boost protein synthesis and cellular activity. Maximum protective effects occur during aging.

LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid cationic peptide derived from hCAP18 that exhibits broad-spectrum antimicrobial activity against bacteria, viruses, and fungi while modulating immune responses.

NA-Selank Amidate is an enhanced version of Selank, the anxiolytic nootropic peptide developed at Russia's Institute of Molecular Genetics. The N-acetyl group improves blood-brain barrier penetration and creates more stable metabolites, while the C-terminal amidation further enhances metabolic stability and receptor binding. Unlike benzodiazepines, it provides anxiety relief without sedation, dependency, or cognitive impairment.

Naltrexone is an opioid receptor antagonist originally developed and FDA-approved at full dose (50 mg) for the treatment of opioid and alcohol use disorders. At this dose, it competitively blocks mu-opioid receptors, preventing the euphoric and reinforcing effects of opioids and reducing alcohol cravings. However, naltrexone has gained enormous popularity in the biohacking and functional medicine communities at dramatically lower doses (1-4.5 mg), commonly referred to as Low-Dose Naltrexone (LDN). At these sub-therapeutic doses, naltrexone produces a brief, transient blockade of opioid receptors lasting only a few hours, which triggers a compensatory upregulation of endogenous endorphins and enkephalins. This rebound effect, combined with direct modulation of the Opioid Growth Factor (OGF) - OGF receptor axis, produces broad anti-inflammatory and immunomodulatory effects that have shown promise across a wide range of autoimmune, inflammatory, and chronic pain conditions.

Rapamycin (sirolimus) is a macrolide compound originally discovered in 1972 from a soil bacterium (Streptomyces hygroscopicus) found on Easter Island (Rapa Nui). It was FDA-approved in 1999 as an immunosuppressant for the prevention of organ transplant rejection and has since become the most studied pharmacological intervention for lifespan extension. Rapamycin is the only drug that has consistently extended lifespan in every organism tested, including yeast, worms, flies, and mice, making it the benchmark compound in longevity research. At immunosuppressive doses (daily administration), it prevents transplant rejection and treats certain cancers. At lower pulsed doses (weekly administration), it is increasingly used off-label in the longevity community to target aging-related pathways while minimizing immunosuppressive side effects. The distinction between daily immunosuppressive dosing and weekly pulsed longevity dosing is critical, as the side effect profiles differ substantially between these two regimens.

Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences. It provides anxiolytic effects comparable to benzodiazepines but without sedation, amnesia, tolerance, or withdrawal.

Thymalin is a natural peptide bioregulator derived from calf thymus gland, developed in the Soviet Union in the 1970s. It contains a mixture of thymic peptides that support immune restoration, anti-aging, and tissue regeneration. Research spanning decades has shown significant geroprotective effects, with studies demonstrating up to 2-fold reduction in mortality rates and 4-fold reduction when combined with Epithalamin.

Thymogen (EW dipeptide) is a Khavinson bioregulator consisting of glutamic acid and tryptophan, originally isolated from calf thymus extracts (Thymalin) in the late 1980s. Developed by Professor Vladimir Khavinson, it has been registered in Russia since 1990 in multiple forms including injectable solution, nasal spray, and topical cream. Thymogen modulates both humoral and cellular immunity, activates T-cell differentiation, and has demonstrated geroprotective (anti-aging) and antitumor activities in research studies.

Thymosin Alpha 1 is a synthetic 28-amino acid peptide identical to naturally occurring thymic hormone, studied in 11,000+ patients across 30+ clinical trials with less than 1% serious adverse events. Approved in 35+ countries for immune modulation.

Naturally occurring 43-amino acid peptide crucial for tissue repair, wound healing, and cellular regeneration. Promotes angiogenesis, reduces inflammation, and supports cell migration and differentiation.

Thymulin is a nonapeptide hormone exclusively secreted by thymic epithelial cells, discovered by Jean-François Bach in the 1970s. Unlike thymalin (a peptide extract mixture), thymulin is a single, defined 9-amino-acid peptide that requires zinc binding for biological activity. It plays a crucial role in T-cell differentiation and maturation within the thymus. Serum thymulin levels decline significantly with age and zinc deficiency, contributing to age-related immune decline (immunosenescence). Research has explored thymulin's potential in restoring immune function, managing autoimmune conditions, and as an anti-inflammatory agent.

Vilon is a Khavinson bioregulator dipeptide (KE) consisting of lysine and glutamic acid, originally isolated from thymus gland extracts. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it acts as a molecular signaling compound that restores normal gene expression and protein synthesis in immune and epithelial cells. Research shows Vilon increases mean lifespan by 20-40% in animal studies and suppresses tumor development.

Vasoactive Intestinal Peptide (VIP) is a 28-amino acid neuropeptide belonging to the glucagon/secretin superfamily. It is produced in many tissues including the gut, pancreas, and brain. VIP has potent vasodilatory, anti-inflammatory, and immunomodulatory effects. It binds to VPAC1 and VPAC2 receptors, triggering cAMP-mediated signaling cascades. Research shows therapeutic potential for pulmonary hypertension, diabetes, neurological disorders, and autoimmune conditions.