Metabolik Sağlık İçin En İyi Bileşikler
İnsülin duyarlılığı, glikoz düzenlemesi ve metabolik sendrom için çalışılan bileşikler.
28 bileşik etkinliğe göre sıralandı
Semaglutide
FDA ApprovedGLP-1 Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: ~7 days (168 hours)
Tirzepatide
FDA ApprovedDual GIP/GLP-1 Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: ~5 days (120 hours)
Retatrutide
Extensively StudiedTriple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes
Yarı ömür: ~6 days
Metformin
FDA ApprovedBiguanide | AMPK Activator & Longevity Research
Yarı ömür: ~5 hours
MOTS-c
Well StudiedMitochondrial-Derived Peptide | Metabolic Regulator
Yarı ömür: ~30 minutes
SLU-PP-332
EmergingSynthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator
Yarı ömür: Under investigation (no human PK data)
NAD+
Extensively StudiedEssential Cellular Coenzyme & Anti-Aging Therapy
Yarı ömür: 1-4 hours (intracellular)
Survodutide
Extensively StudiedDual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: Approximately 6 days (109-115 hours)
Mazdutide
Extensively StudiedDual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: 6-8 days
AICAR
limited5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator
Yarı ömür: ~2-3 hours
Cagrilintide
Extensively StudiedLong-Acting Amylin Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: ~7 days (159-195 hours)
Orforglipron
Extensively StudiedOral Small-Molecule GLP-1 Receptor Agonist | Weight Loss & Diabetes
Yarı ömür: 25-68 hours
L-Carnitine
establishedAmino Acid Derivative | Fatty Acid Transporter
Yarı ömür: ~2-3 hours (injectable)
Tesamorelin
FDA ApprovedGHRH Analog | Visceral Fat Reduction
Yarı ömür: 26-38 minutes
Testosterone
FDA ApprovedAnabolic-Androgenic Steroid | Primary Male Sex Hormone
Yarı ömür: ~8 days (cypionate)
Berberine
Moderate ResearchPlant Alkaloid | Natural Glucose & Lipid Management
Yarı ömür: ~4 hours
VIP
Extensively StudiedVasoactive Intestinal Peptide | Neuropeptide
Yarı ömür: 1-2 minutes
BAM-15
Moderate ResearchMitochondrial Uncoupler | Metabolic Enhancer
Yarı ömür: ~1.7 hours
5-Amino-1MQ
preclinicalNNMT Inhibitor | Longevity & Metabolic Enhancement
Yarı ömür: 4-7 hours (3.8h IV, 6.9h oral)
Hexarelin
Well StudiedExamorelin | Synthetic Growth Hormone Secretagogue
Yarı ömür: 1-2 hours
NMN
Moderate ResearchNAD+ Precursor | Cellular Energy & Longevity
Yarı ömür: ~2-3 hours (oral)
Pancragen
Moderate ResearchKEDW Tetrapeptide | Pancreas Bioregulator
Yarı ömür: Not established
Telmisartan
FDA ApprovedAngiotensin II Receptor Blocker | Cardiac Protection On Cycle
Yarı ömür: ~24 hours
Melanotan II
Well StudiedSynthetic Melanocortin Peptide | Tanning & Sexual Function
Yarı ömür: ~2 hours
Cyclic Glycine-Proline
Moderate ResearchIGF-1 Bioavailability Regulator & Neuroprotective Peptide
Yarı ömür: Extended stability (more stable than linear GPE precursor)
IGF-1 LR3
limitedModified Growth Factor Analog | Muscle Growth
Yarı ömür: 20-30 hours
Adipotide
EmergingProhibitin-Targeting Peptidomimetic | Experimental Anti-Obesity
Yarı ömür: Not established
Kisspeptin
EmergingKISS1 Gene Product | Reproductive Neuropeptide
Yarı ömür: ~4 minutes (KP-10), ~28-32 minutes (KP-54)