DSA

Metabolik Sağlık İçin En İyi Bileşikler

İnsülin duyarlılığı, glikoz düzenlemesi ve metabolik sendrom için çalışılan bileşikler.

28 bileşik etkinliğe göre sıralandı

01

Semaglutide

FDA Approved

GLP-1 Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: ~7 days (168 hours)

02

Tirzepatide

FDA Approved

Dual GIP/GLP-1 Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: ~5 days (120 hours)

03

Retatrutide

Extensively Studied

Triple GLP-1/GIP/Glucagon Agonist | Weight Loss & Diabetes

Yarı ömür: ~6 days

04

Metformin

FDA Approved

Biguanide | AMPK Activator & Longevity Research

Yarı ömür: ~5 hours

05

MOTS-c

Well Studied

Mitochondrial-Derived Peptide | Metabolic Regulator

Yarı ömür: ~30 minutes

06

SLU-PP-332

Emerging

Synthetic Pan-ERR Agonist | Exercise Mimetic & Metabolic Modulator

Yarı ömür: Under investigation (no human PK data)

07

NAD+

Extensively Studied

Essential Cellular Coenzyme & Anti-Aging Therapy

Yarı ömür: 1-4 hours (intracellular)

08

Survodutide

Extensively Studied

Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: Approximately 6 days (109-115 hours)

09

Mazdutide

Extensively Studied

Dual GLP-1/Glucagon Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: 6-8 days

10

AICAR

limited

5-Aminoimidazole-4-carboxamide Ribonucleotide | AMPK Activator

Yarı ömür: ~2-3 hours

11

Cagrilintide

Extensively Studied

Long-Acting Amylin Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: ~7 days (159-195 hours)

12

Orforglipron

Extensively Studied

Oral Small-Molecule GLP-1 Receptor Agonist | Weight Loss & Diabetes

Yarı ömür: 25-68 hours

13

L-Carnitine

established

Amino Acid Derivative | Fatty Acid Transporter

Yarı ömür: ~2-3 hours (injectable)

14

Tesamorelin

FDA Approved

GHRH Analog | Visceral Fat Reduction

Yarı ömür: 26-38 minutes

15

Testosterone

FDA Approved

Anabolic-Androgenic Steroid | Primary Male Sex Hormone

Yarı ömür: ~8 days (cypionate)

16

Berberine

Moderate Research

Plant Alkaloid | Natural Glucose & Lipid Management

Yarı ömür: ~4 hours

17

VIP

Extensively Studied

Vasoactive Intestinal Peptide | Neuropeptide

Yarı ömür: 1-2 minutes

18

BAM-15

Moderate Research

Mitochondrial Uncoupler | Metabolic Enhancer

Yarı ömür: ~1.7 hours

19

5-Amino-1MQ

preclinical

NNMT Inhibitor | Longevity & Metabolic Enhancement

Yarı ömür: 4-7 hours (3.8h IV, 6.9h oral)

20

Hexarelin

Well Studied

Examorelin | Synthetic Growth Hormone Secretagogue

Yarı ömür: 1-2 hours

21

NMN

Moderate Research

NAD+ Precursor | Cellular Energy & Longevity

Yarı ömür: ~2-3 hours (oral)

22

Pancragen

Moderate Research

KEDW Tetrapeptide | Pancreas Bioregulator

Yarı ömür: Not established

23

Telmisartan

FDA Approved

Angiotensin II Receptor Blocker | Cardiac Protection On Cycle

Yarı ömür: ~24 hours

24

Melanotan II

Well Studied

Synthetic Melanocortin Peptide | Tanning & Sexual Function

Yarı ömür: ~2 hours

25

Cyclic Glycine-Proline

Moderate Research

IGF-1 Bioavailability Regulator & Neuroprotective Peptide

Yarı ömür: Extended stability (more stable than linear GPE precursor)

26

IGF-1 LR3

limited

Modified Growth Factor Analog | Muscle Growth

Yarı ömür: 20-30 hours

27

Adipotide

Emerging

Prohibitin-Targeting Peptidomimetic | Experimental Anti-Obesity

Yarı ömür: Not established

28

Kisspeptin

Emerging

KISS1 Gene Product | Reproductive Neuropeptide

Yarı ömür: ~4 minutes (KP-10), ~28-32 minutes (KP-54)

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